Mile ratingNo known defect pattern for this model year
The 2022 Mercedes-Benz E-Class is not on our list of model years with a widely reported mechanical or electrical problem. That is a point in its favour, not a clean bill of health — this car's own history still matters, so check the VIN report and get it inspected.
What owners of the 2022 E-Class say
Owner reviews for this exact model year are the fastest way to find out what breaks, what it costs to fix and whether the car lives up to the spec sheet.
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About this car
The Mercedes-Benz E-Class is No. 45 on the Caboose longevity table: 7% of them reach 250,000 miles, against 5.4% of all vehicles. This 2022 Mercedes-Benz E-Class E 350 RWD is listed at $33,009, about $2,817 below the CarGurus expected market price of $35,826. It has 24,028 miles and comes in Cirrus Silver Metallic. Power comes from a 255 hp 2L I4 with rear-wheel drive, rated around 27 MPG combined. It is offered by K&S Acura and Alfa Romeo in San Diego, CA (franchise dealer).
Why it's a good buy
- 7% of Mercedes-Benz E-Classs reach 250,000 miles — No. 45 of 52 on the Caboose table
- 175,972 miles of runway before 200,000
- 8% below market price ($2,817 savings)
- Below-average mileage for its age
- No widely reported defect pattern for this model year
- Sport Package
Features
Caboose PRO
The full 776-word analysis of this car
The verdict
The 2022 Mercedes-Benz E-Class E 350 RWD is listed at $33,009 with 24,028 miles. The Caboose score is 8.6 out of 10, built from three things: how far below market the price sits, how much of the 200,000-mile target is still ahead of the odometer, and how often this model reaches 250,000 miles in the iSeeCars study (7% of Mercedes-Benz E-Classs do).
The asking price is $2,817 (7.9%) under the CarGurus expected price of $35,826, which is a real discount rather than a rounding gap. That puts it in the top group of cars on this site, so it is worth a same-week inspection before someone else books one.
- Price against the market
- Mileage runway to 200,000
- Odds of reaching 250,000 miles
- Ownership budget (planning estimates)
- What to inspect on this exact car
- Questions for K&S Acura and Alfa Romeo
- Your next seven days
Get it road-ready
The usual first-week purchases for a 2022 Mercedes-Benz E-Class, from partners we trust.
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